Aderis Pharmaceuticals
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Aderis Pharmaceuticals is committed to improving clinical outcomes and quality of life for people living with devastating CNS, cardiovascular and inflammatory conditions. Our expertise in sub-type specific receptor technologies allows us to quickly develop new and effective pharmaceuticals. Since our founding in 1994, we have already developed 7 proprietary small molecule product candidates for multiple indications. Five are currently in development focused on nine indication areas. Aderis, although focused in cardiovascular diseases, is also developing other "opportunistic" projects that utilize the company's expertise and fill a therapeutic void in important areas of medicine.

Though none of our products are designed to cure disease, each alleviates painful, debilitating symptoms and enables patients to live more normal and fulfilling lives.

Corporate collaborations are an integral part of our development and growth strategy. Aderis has development and commercialization agreements with Schwarz Pharma for Rotigotine, with King Pharmaceuticals for Binodenoson and MRE-0094 and Canfite BioPharma for CF101.

ADERIS' Internal & Partnered Product Pipeline
Product Candidates Indications Receptors Subtype Estimated Patient Population
Neupro™
Rotigotine
Parkinson's
disease
Dopamine
Agonist
4 million WW
Rotigotine Restless Legs Syndrome Dopamine
Agonist
12 million US
Rotigotine Nasal Rescue therapy for Parkinson's
disease
Dopamine
Agonist
4 million WW
Binodenoson (MRE-0470) Cardiac Diagnosis Adenosine A2A Agonist 2.6 million tests/year in US
Selodenoson
(DTI-0009)
Atrial Fibrillation Adenosine A1 Agonist 6 million WW
MRE-0094 Wound healing in
diabetic foot ulcers
Adenosine A2A Agonist 22 million in US
CF101 Colorectal Cancer and Rheumatoid Arthritis Adenosine A3
Agonist
 

ADERIS' Internal & Partnered Development Status
Product Candidates Pre-Clinical Phase I Phase II Phase III NDA
Neupro™
(Rotigotine)
Early Stage Parkinson's Disease
Rotigotine
Advanced Stage Parkinson's Disease
Rotigotine
Restless Leg Syndrome
Binodenoson (MRE-0470)
Selodenoson-IV
Selodenoson-SR
Rotigotine Nasal
Rescue Parkinson's Disease
MRE-0094
CF101
Colorectal Cancer
CF101
Rheumatoid Arthritis

For more information on any product candidate or disease indication, please click on the corresponding product or disease name in the chart above.




"In the pharmaceutical industry, it's a well known but seldom emphasized fact that only 10% of products entering Phase I clinical trials ever achieve FDA approval - that's why a broad product pipeline is key to the success of any biopharmaceutical company. At Aderis, our robust pipeline is one of our greatest strengths; we have products for 6 indications in clinical trials."

-William Wheeler, MD,
Chief Medical Officer, Aderis Pharmaceuticals




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